Inflammation

April 26, 2017April 26, 2017

Researchers Find 2 Potential Molecules for Fighting Rheumatoid Arthritis, Other Inflammatory Diseases

Greek researchers have found two molecules — T23 and T8 — that show promise in treating rheumatoid arthritis and other chronic inflammatory diseases. Both molecules act against tumor necrosis ... Read more

April 12, 2017April 12, 2017

Obesity May Alter Diagnosis, Management of RA When Blood Tests Are Used

News, rheumatoid arthritis

Obesity in women may interfere with the diagnosis and monitoring of rheumatoid arthritis (RA) through blood tests, according to a new study. Researchers call for more attention to the ... Read more

March 17, 2017March 17, 2017

EULAR Recommends Use of JAK Inhibitors, Including Xeljanz, for RA Management

News, rheumatoid arthritis

The European League Against Rheumatism (EULAR) has recommended the use of janus kinase (JAK) protein inhibitors, such as Pfizer’s Xeljanz (tofacitinib citrate), for the management of rheumatoid arthritis (RA). EULAR’s ... Read more

March 8, 2017March 8, 2017

Cytokine IL-21 Fuels Inflammation at Synovial Joints in RA Patients, Study Shows

News, rheumatoid arthritis

Scientists have discovered a group of immune cells that cause joint inflammation in rheumatoid arthritis (RA) by secreting a factor called interleukin (IL)-21 — a potential new target for RA therapeutics. The ... Read more

February 8, 2017February 8, 2017

Sanofi’s Kevzara Approved in Canada as Treatment for Moderate to Severe RA

News

Kevzara (sarilumab) has been approved in Canada as a treatment for adult patients with moderate to severe rheumatoid arthritis (RA) who are either intolerant or considered inappropriate candidates to be ... Read more

February 6, 2017February 6, 2017

Newly Identified T-cell in RA Patients May Leapfrog Autoimmune Treatment Development

News, rheumatoid arthritis

An entirely new type of T-cell found in people with rheumatoid arthritis works in a unique way to drive disease processes in the joints by teaming up with other ... Read more

January 27, 2017January 27, 2017

Real-time Imaging Used to Identify Protein That Triggers Inflammatory Arthritis

News

Using a novel imaging technique, researchers followed in real time the movement of immune cells in a live mouse and identified a key factor responsible for triggering inflammatory arthritis. ... Read more

January 23, 2017January 23, 2017

Targeting SCIMP Protein Shows Potential in Inflammatory Diseases Like RA

News

The ability to reduce or “switch off” inflammation may be possible thanks to a new discovery made by researchers at the University of Queensland (UQ) in Australia. They found that ... Read more

January 16, 2017January 16, 2017

RA Treatment with TNF Inhibitors Greatly Decreases Heart Attack Risk, UK Study Finds

News

The risk of heart attack associated with rheumatoid arthritis (RA) may decrease by nearly half when TNF inhibitors (TNFi) are part of the treatment, according to new research conducted ... Read more

December 21, 2016December 21, 2016

JAK-1 Inhibitor, ABT-494, Seen to Aid RA Patients Now Advancing into Phase 3 Tests

News

Recent results from a Phase 2b clinical trial evaluating the JAK-1 inhibitor, ABT-494, in patients with moderate to severe rheumatoid arthritis (RA) who did not respond to methotrexate (MTX) therapy ... Read more

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